Can you overdose on epilim?

Cases of accidental and deliberate Epilim overdose have been reported. At plasma concentrations of up to 5 – 6 times the maximum therapeutic levels, there are unlikely to be any symptoms other than nausea, vomiting and dizziness.

What does epilim do to the body?

Epilim contains sodium valproate. It belongs to a group of medicines called anti-convulsants or anti-epileptic agents. It works by helping to calm the brain down. Epilim is used to treat epilepsy (fits) in adults and children.

How does epilim make you feel?

Epilim may cause drowsiness, dizziness or sleepiness in some people and affect alertness. Diabetics are advised that Epilim Syrup contains 3.6 g/5 mL of sucrose (sugar). The effects of alcohol could be made worse while taking Epilim. Combining it and alcohol can make you more sleepy, dizzy or lightheaded.

What are the main side effects of sodium valproate?

Common side effects

• stomach pain, feeling or being sick.
• diarrhoea.
• dry or sore mouth, or swollen gums.
• shakes (tremors) in a part of your body, or unusual eye movements.
• feeling tired or sleepy.
• headache.
• weight gain.
• thinning hair, or changes to the colour or texture of your hair.

Does epilim make you aggressive?

The authors point out that as side effects of sodium valproate can include aggression, hyperactivity and behavioural disturbances, then if it is prescribed for the treatment of bipolar disorder with co-occurring behavioural disturbances, it is possible that the medication may make these behaviours worse.

How much sodium valproate is too much?

Sodium valproate dose response relationship: 200 to 400 mg/kg — moderate toxicity with CNS depression. >400 mg/kg — risk of multi-organ system toxicities. >1000 mg/kg — coma, multi-organ failure, cerebral oedema, potentially life-threatening.

Can epilim cause heart problems?

But a recent study by the University of Liverpool also revealed a link between the drug and other developmental problems in children. The drug has been around since the mid-seventies and can cause heart problems and a range of physical deformities, such as spina bifida and cleft lip in unborn babies.

Does epilim calm you down?

Epilim Chrono contains sodium valproate. It belongs to a group of medicines called anti-convulsants or anti-epileptic agents. It works by helping to calm the brain down. Epilim Chrono is used to treat epilepsy (fits) in adults and children.

Does epilim make you angry?

Can epilim cause shaking?

Approximately 25\% of patients taking valproate are found to develop a tremor within 3–12 months of initiating therapy. The tremor is often observed with action or postural in nature, although a resting tremor may occur. The tremor is often fine in nature and can affect a patient’s head, mouth, tongue, and limbs.

Does epilim put on weight?

Weight gain is a well-known adverse effect of VPA treatment, occurring in 40\% of children. Weight gain is the most common reason for patients to discontinue VPA treatment.

Can you overdose on valproate?

Conclusions. Valproate causes mild toxicity in the majority of cases. Massive overdoses of greater than 400 mg kg−1 can cause severe toxicity, but these are uncommon. The older anticonvulsants phenytoin and carbamazepine remain a greater problem than valproate in overdose.