How much clomipramine should I take for OCD?

Adult dose: The initial dose for adults is 25mg daily, as a single dose, however, it may be started at a lower dose and increased gradually over 2 weeks to 100–150 mg and up to a maximum of 250 mg per day.

How effective is escitalopram for OCD?

Escitalopram has an average rating of 8.5 out of 10 from a total of 91 ratings for the treatment of Obsessive Compulsive Disorder. 80\% of reviewers reported a positive effect, while 8\% reported a negative effect.

Is clomipramine best for OCD?

The tricyclic antidepressant clomipramine was the first agent shown clearly to be beneficial in patients with OCD [4]; it was approved by the FDA for the treatment of OCD in 1989. Of the tricyclics, clomipramine is the most potent inhibitor of serotonin reuptake.

What is best SSRI for OCD?

Four SSRIs that have been shown to be effective in treating OCD and are FDA-approved to treat adults with OCD in the United States are: Sertraline (brand name Zoloft) Fluoxetine (brand name Prozac) Fluvoxamine (brand name Luvox)

How long does clomipramine take to work for OCD?

When will clomipramine start working? When used to treat OCD, clomipramine may need to be taken for 6 to 12 weeks before you notice an improvement in your symptoms. It may take 4 to 6 months to see the full effect of this medication.

Which is better for OCD Lexapro or Prozac?

When comparing Lexapro to Prozac, the authors found both drugs to be similarly effective. Another study, which was a review of many studies, compared antidepressants and initially found Lexapro to possibly be more effective and better tolerated than other antidepressants.

What is the most effective SSRI for OCD?

Action Points. Explain to interested patients that antidepressants, such as fluoxetine (Prozac) and sertraline (Zoloft), were modestly effective for controlling the symptoms of obsessive compulsive disorder, according to a study review.

Is clomipramine better than SSRI?

Clomipramine was significantly more effective than each of the SSRIs (pooled effects comparison; clomipramine v paroxetine p = 0.003; v fluoxetine p<0.03; v fluvoxamine p = 0.001; v sertraline p<0.001). There was no significant difference between any of the individual SSRIs.

What is the highest dose of escitalopram you can take?

This study explored the efficacy and tolerability of very high doses (maximum dose of >40 mg/day), high doses (maximum dose of 25-40 mg/day), and standard doses (maximum dose of ≤20 mg/day) of escitalopram (ESC) as an anti-obsessive-compulsive disorder treatment in a naturalistic clinical setting …

Is it safe to take fluvoxamine and clomipramine together?

Comedications with SSRIs, however, may be hazardous owing to pharmacokinetic interactions that can result in elevated serum TCA levels. For the combinations, safety and tolerability data are lacking. Method: We report tolerability and safety of combined treatment with fluvoxamine and clomipramine (CMI) in 22 patients.

Should SSRIs be combined with tricyclic antidepressants to treat depression?

Background: Combination treatment with tricyclic antidepressants (TCAs) and serotonin selective reuptake inhibitors (SSRIs) is an increasingly employed strategy especially in depressed patients unresponsive to monotherapy.