What does B6 toxicity feel like?

Patients may experience unsteadiness of gait, incoordination (ataxia), involuntary muscle movements (choreoathetosis) the sensation of an electric zap in their bodies (Lhermitte’s sign), a heightened sensitivity to sense stimuli including photosensitivity (hyperesthesia), impaired skin sensation (hypoesthesia).

How do you treat vitamin B6 toxicity?

There is no specific treatment or antidote for pyridoxine toxicity. Treatment involves cessation of supplemental pyridoxine promptly following diagnosis, symptomatic management, and supportive care for any continued or irreversible symptoms. This could include physical therapy when appropriate.

What happens when your B6 is high?

Taking very high doses of vitamin B6 may damage the nerves (called neuropathy. Infections, toxins, drugs, cancers, nutritional deficiencies, diabetes, autoimmune disorders, and… read more ), causing pain and numbness in the feet and legs.

Is vitamin B6 toxicity reversible?

In most instances, the clinical signs of toxicity were reversible once ingestion of high doses of vitamin B6 had ceased. However, in some instances where the dose of this vitamin was especially high, signs of damage remained.

How long does it take to recover from B6 toxicity?

Very high doses, 200 mg or more per day, of vitamin B6 can cause neurological disorders, such as loss of feeling in the legs and imbalance. Stopping high doses usually leads to a complete recovery within 6 months.

What happens if you take too much vitamin B?

When a higher dose of vitamin B is taken, people may suffer from indigestion, nausea or mild diarrhea. People with a prior history of gastrointestinal problems and aged individuals are more likely to suffer from intense stomach cramps and severe diarrhea after taking high doses of vitamin B.

Do you pee out excess B6?

The body does not store vitamin B6 and releases any excess in urine, so people need to get enough vitamin B6 every day. This article looks at the health benefits and food sources of vitamin B6, along with a person’s daily needs of the vitamin. It also discusses deficiency and supplements.

What is considered a toxic level of B6?

There have also been occasional reports of toxicity at intakes of 100-300 mg per day. The US authorities set the no-observed-adverse-effect-level at 200 mg per day and the safe upper limit at 100 mg per day.

Can too much B6 cause tingling?

A known side effect of vitamin B6 is peripheral neuropathy, which has symptoms of tingling, burning or numbness, usually in the hands or feet. It usually occurs at high doses or following long-term use of products containing vitamin B6.

How much B6 is too much?

Taking more than 1,000 mg of supplemental B6 a day may cause nerve damage and pain or numbness in the hands or feet. Some of these side effects have even been documented after just 100–300 mg of B6 per day ( 49 ). For these reasons, the tolerable upper limit of vitamin B6 is 100 mg per day for adults (3, 50 ).

What causes elevated B6 levels?

Elevated B6 levels and peripheral neuropathies. The most common symptoms reported were numbness (96\%), burning pain (49.9\%), tingling (57.7\%), balance difficulties (30.7\%), and weakness (7.8\%). Nine (out of 26) had an abnormal EMG/NCS. Eight patients had an abnormal quantitative sensory study.

What causes high B6?

High levels of vitamin B6 can cause neurological disorders and numbness. Deficiency of vitamin B6 can cause mouth and tongue sores, irritability, confusion, and depression. Good sources of Vitamin B6 include nuts, legumes, eggs, meats, fish, whole grains, and fortified breads and cereals.

What are the side effects of B – 6?

Although vitamin B6 is necessary for healthy nerve function, it may cause side effects that also affect the nervous system. A possible side effect of vitamin B6 supplementation is decreased sensation. Specifically, you may notice numbness around the feet or mouth, a decreased sensation to touch or tingling in the skin.